Transactions disclosed by company insiders to the SEC on Form 4, most recent first.
| Insider | Role | Date | Shares | Value |
|---|---|---|---|---|
| Adsett Roger | Chief Operating Officer | 2026-08-10 | 82,280 | $1,124,768 |
| Adsett Roger | Chief Operating Officer | 2026-08-10 | 76,600 | $1,314,456 |
| Adsett Roger | Chief Operating Officer | 2026-08-10 | 80,970 | $2,466,346 |
| Adsett Roger | Chief Operating Officer | 2026-08-10 | 239,850 | $31,964,810 |
| Flammer Martina M.D. | Chief Medical Officer | 2026-08-06 | 18,278 | $346,368 |
| Flammer Martina M.D. | Chief Medical Officer | 2026-08-06 | 8,895 | $229,758 |
| Flammer Martina M.D. | Chief Medical Officer | 2026-08-06 | 8,895 | $1,129,665 |
| Flammer Martina M.D. | Chief Medical Officer | 2026-08-06 | 18,278 | $2,365,173 |
| Lewis William | Chair and CEO | 2026-07-23 | 6,260 | $190,680 |
| Lewis William | Chair and CEO | 2026-07-23 | 4,440 | $76,190 |
Position changes disclosed in SEC Form 13F filings. These report a quarterly snapshot, not exact trade dates.
| Fund | Change | Quarter |
|---|---|---|
| NORGES BANK | NORGES BANK opened a new position worth $360,124,083. | 2026-06-30 |
| JPMORGAN CHASE & CO | JPMORGAN CHASE & CO opened a new position worth $285,521. | 2026-06-30 |
| Prosight Management, LP | Prosight Management, LP opened a new position worth $40,047,432. | 2026-06-30 |
| Railway Pension Investments Ltd | Railway Pension Investments Ltd opened a new position worth $64,473,114. | 2026-06-30 |
| MAVERICK CAPITAL LTD | MAVERICK CAPITAL LTD opened a new position worth $229,314,244. | 2026-06-30 |
| AQR CAPITAL MANAGEMENT LLC | AQR CAPITAL MANAGEMENT LLC increased this position by 229774% ($28,408 -> $65,302,719). | 2026-06-30 |
| TWO SIGMA INVESTMENTS, LP | TWO SIGMA INVESTMENTS, LP increased this position by 242% ($38,757,020 -> $132,445,710). | 2026-06-30 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | SUSQUEHANNA INTERNATIONAL GROUP, LLP increased this position by 174% ($28,391,978 -> $77,763,723). | 2026-06-30 |
Largest reported positions as of 2026-06-30.
| Fund | Value | Shares |
|---|---|---|
| FMR LLC | $1,246,915,143 | 11,694,946 |
| VANGUARD PORTFOLIO MANAGEMENT LLC | $1,109,696,908 | 10,407,962 |
| VANGUARD CAPITAL MANAGEMENT LLC | $1,043,902,026 | 9,790,865 |
| BAKER BROS. ADVISORS LP | $937,841,355 | 8,796,111 |
| Capital International Investors | $878,338,960 | 8,238,124 |
| Darwin Global Management, Ltd. | $673,600,013 | 6,431,163 |
| Artisan Partners Limited Partnership | $580,195,955 | 5,441,718 |
| RTW INVESTMENTS, LP | $516,347,866 | 4,842,880 |
| AMERIPRISE FINANCIAL INC | $483,856,150 | 4,538,102 |
| GEODE CAPITAL MANAGEMENT, LLC | $389,229,811 | 3,661,786 |
Data compiled from public SEC filings. This is informational reporting, not investment advice.
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